| 1. Round | 23/07/2021 | FC Juárez [U18] | - | Deportivo Toluca [U18] | 1:2 |  |
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| 2. Round | 31/07/2021 | Atlas Guadalajara [U18] | - | FC Juárez [U18] | 2:1 | ||||
| 3. Round | 07/08/2021 | Deportivo Guadalajara [U18] | - | FC Juárez [U18] | 1:2 | ||||
| 4. Round | 13/08/2021 | FC Juárez [U18] | - | Club Tijuana [U18] | 3:2 | |
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| 5. Round | 18/08/2021 | FC Juárez [U18] | - | CF América [U18] | 2:2 | ||||
| 7. Round | 29/08/2021 | Santos Laguna [U18] | - | FC Juárez [U18] | 0:0 | ||||
| 8. Round | 10/09/2021 | FC Juárez [U18] | - | Cruz Azul [U18] | 5:0 | ||||
| 14. Round | 21/09/2021 | FC Juárez [U18] | - | Atlético San Luis [U18] | 0:3 | ||||
| 10. Round | 24/09/2021 | FC Juárez [U18] | - | Gallos Blancos [U18] | 0:0 |  |
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| 11. Round | 28/09/2021 | Mazatlán FC [U18] | - | FC Juárez [U18] | 3:2 | ||||
| 12. Round | 01/10/2021 | FC Juárez [U18] | - | CF Monterrey [U18] | 3:0 | ||||
| 13. Round | 17/10/2021 | Pumas UNAM [U18] | - | FC Juárez [U18] | 2:0 | ||||
| 15. Round | 25/10/2021 | CF Pachuca [U18] | - | FC Juárez [U18] | 3:0 | ||||
| 16. Round | 29/10/2021 | FC Juárez [U18] | - | Puebla FC [U18] | 0:2 | ||||
| 17. Round | 06/11/2021 | UANL Tigres [U18] | - | FC Juárez [U18] | 2:0 |
Mexico