| 1. Round | 11/02/2022 | Central Córdoba SdE II | - | Barracas Central II | 5:1 | ||||
| 2. Round | 16/02/2022 | Lanús II | - | Barracas Central II | 0:2 | ||||
| 3. Round | 20/02/2022 | Barracas Central II | - | Tigre II | 0:4 | ||||
| 4. Round | 25/02/2022 | Colón de Santa Fe II | - | Barracas Central II | 3:2 | ||||
| 5. Round | 04/03/2022 | Barracas Central II | - | Aldosivi II | 0:2 | ||||
| 6. Round | 11/03/2022 | Rosario Central II | - | Barracas Central II | 1:2 |  |
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| 7. Round | 18/03/2022 | Barracas Central II | - | Sarmiento de Junín II | 0:2 | ||||
| 8. Round | 03/04/2022 | Barracas Central II | - | Independiente II | 3:1 | ||||
| 9. Round | 08/04/2022 | Huracán II | - | Barracas Central II | 5:0 | ||||
| 10. Round | 13/04/2022 | Barracas Central II | - | Estudiantes II | 2:2 | ||||
| 11. Round | 18/04/2022 | Arsenal de Sarandí II | - | Barracas Central II | 0:0 | ||||
| 12. Round | 24/04/2022 | Barracas Central II | - | Vélez Sarsfield II | 0:0 | ||||
| 13. Round | 29/04/2022 | Boca Juniors II | - | Barracas Central II | 2:0 | ||||
| 14. Round | 09/05/2022 | Barracas Central II | - | Godoy Cruz II | 0:2 |
Argentina