| 14. Round | 16/01/2022 | Pau FC [Youth B] | - | Nîmes Olympique [Youth B] | 3:2 |  |
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| 16. Round | 06/02/2022 | Pau FC [Youth B] | - | Rodez AF [Youth B] | 0:1 | ||||
| 17. Round | 12/02/2022 | Girondins Bordeaux [Youth B] | - | Pau FC [Youth B] | 2:1 | ||||
| 15. Round | 20/02/2022 | Montpellier HSC [Youth B] | - | Pau FC [Youth B] | 2:1 | ||||
| 18. Round | 06/03/2022 | Pau FC [Youth B] | - | Montauban FC [Youth B] | 4:1 | ||||
| 19. Round | 13/03/2022 | Balma SC [Youth B] | - | Pau FC [Youth B] | 5:0 | ||||
| 26. Round | 15/05/2022 | AC Vedène [Youth B] | - | Pau FC [Youth B] | 2:1 |
France