| 5. Round | 04/09/2021 | US Granvillaise | - | SO Romorantin | 1:2 | ||||
| 6. Round | 11/09/2021 | FC Rouen 1899 | - | US Granvillaise | 0:2 | ||||
| 7. Round | 18/09/2021 | US Granvillaise | - | AS Vitré | 1:1 |  |
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| 8. Round | 25/09/2021 | FC Versailles | - | US Granvillaise | 0:0 | |
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| 12. Round | 20/11/2021 | Blois Foot 41 | - | US Granvillaise | 2:2 | |
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| 13. Round | 04/12/2021 | US Granvillaise | - | FC Lorient B | 0:0 | ||||
| 14. Round | 11/12/2021 | EA Guingamp B | - | US Granvillaise | 1:0 | |
France