| 5. Round | 09/10/1960 | Real Sociedad | - | Real Oviedo | 2:0 | ||||
| 6. Round | 16/10/1960 | Real Oviedo | - | Elche CF | 4:0 |  |
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| 7. Round | 23/10/1960 | Espanyol Barcelona | - | Real Oviedo | 4:1 | ||||
| 8. Round | 06/11/1960 | Real Oviedo | - | Valencia CF | 2:2 | |
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| 9. Round | 13/11/1960 | Sevilla FC | - | Real Oviedo | 3:2 | ||||
| 10. Round | 20/11/1960 | Real Oviedo | - | Granada CF | 0:0 | ||||
| 23. Round | 26/02/1961 | Valencia CF | - | Real Oviedo | 3:1 | |
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| 24. Round | 05/03/1961 | Real Oviedo | - | Sevilla FC | 2:2 | |
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| 25. Round | 12/03/1961 | Granada CF | - | Real Oviedo | 1:1 | ||||
| 27. Round | 26/03/1961 | Real Zaragoza | - | Real Oviedo | 4:1 | ||||
| 28. Round | 09/04/1961 | Real Oviedo | - | RCD Mallorca | 1:0 | |
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| 29. Round | 23/04/1961 | Real Oviedo | - | Athletic Club | 2:0 | ||||
| 30. Round | 30/04/1961 | FC Barcelona | - | Real Oviedo | 3:5 | |
Spain