| 1. Round | 07/08/2021 | C'Chartres Football | - | US Granvillaise | 2:1 | ||||
| 2. Round | 14/08/2021 | US Granvillaise | - | Châteaubriant Voltigeurs | 0:0 | ||||
| 3. Round | 21/08/2021 | Vannes OC | - | US Granvillaise | 0:0 |  |
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| 4. Round | 28/08/2021 | SM Caen B | - | US Granvillaise | 1:1 | |
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| 5. Round | 04/09/2021 | US Granvillaise | - | SO Romorantin | 1:2 | ||||
| 9. Round | 09/10/2021 | US Granvillaise | - | US Saint-Malo | 1:0 | ||||
| 10. Round | 23/10/2021 | Stade Plabennec | - | US Granvillaise | 3:1 | ||||
| 11. Round | 06/11/2021 | US Granvillaise | - | St-Pryvé St-Hilaire | 2:1 | ||||
| 13. Round | 04/12/2021 | US Granvillaise | - | FC Lorient B | 0:0 |
France