| 1. Round | 07/08/2021 | AS Poissy | - | SO Romorantin | 2:0 | ||||
| 2. Round | 14/08/2021 | SO Romorantin | - | C'Chartres Football | 2:1 | ||||
| 3. Round | 21/08/2021 | Châteaubriant Voltigeurs | - | SO Romorantin | 3:1 | ||||
| 4. Round | 28/08/2021 | SO Romorantin | - | Vannes OC | 1:2 |  |
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| 5. Round | 04/09/2021 | US Granvillaise | - | SO Romorantin | 1:2 | ||||
| 6. Round | 11/09/2021 | SM Caen B | - | SO Romorantin | 0:0 | ||||
| 9. Round | 09/10/2021 | SO Romorantin | - | FC Versailles | 1:3 | ||||
| 10. Round | 23/10/2021 | US Saint-Malo | - | SO Romorantin | 0:2 | |
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| 12. Round | 20/11/2021 | St-Pryvé St-Hilaire | - | SO Romorantin | 1:0 | ||||
| 13. Round | 04/12/2021 | SO Romorantin | - | Blois Foot 41 | 1:1 | ||||
| 14. Round | 11/12/2021 | FC Lorient B | - | SO Romorantin | 4:0 | ||||
| 15. Round | 15/01/2022 | SO Romorantin | - | EA Guingamp B | 2:3 | ||||
| 16. Round | 22/01/2022 | C'Chartres Football | - | SO Romorantin | 1:0 | |
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| 17. Round | 05/02/2022 | SO Romorantin | - | Châteaubriant Voltigeurs | 1:0 | |
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| 18. Round | 12/02/2022 | Vannes OC | - | SO Romorantin | 3:1 | ||||
| 19. Round | 19/02/2022 | SO Romorantin | - | US Granvillaise | 0:2 |
France