| 15. Round | 16/01/2022 | USSA Vertou [Youth] | - | EA Guingamp [Youth] | 1:0 | ||||
| 16. Round | 23/01/2022 | Le Mans FC [Youth] | - | USSA Vertou [Youth] | 0:1 | ||||
| 20. Round | 06/02/2022 | USSA Vertou [Youth] | - | SA Mérignac [Youth] | 1:0 | ||||
| 21. Round | 13/02/2022 | USSA Vertou [Youth] | - | Tours FC [Youth] | 4:0 | ||||
| 22. Round | 06/03/2022 | Girondins Bordeaux [Youth] | - | USSA Vertou [Youth] | 1:0 | ||||
| 25. Round | 01/05/2022 | Stade Lavallois [Youth] | - | USSA Vertou [Youth] | 0:4 | ||||
| 26. Round | 15/05/2022 | USSA Vertou [Youth] | - | Stade Rennais [Youth] | 1:0 |
France