| 9. Round | 16/10/2021 | Stade Brestois 29 [Youth] | - | Stade Lavallois [Youth] | 3:2 |  |
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| 11. Round | 14/11/2021 | Stade Brestois 29 [Youth] | - | Tours FC [Youth] | 4:1 | ||||
| 14. Round | 05/12/2021 | Stade Brestois 29 [Youth] | - | USSA Vertou [Youth] | 5:0 | |
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| 21. Round | 13/02/2022 | Stade Brestois 29 [Youth] | - | LB Châteauroux [Youth] | 1:0 | ||||
| 22. Round | 06/03/2022 | US Avranches [Youth] | - | Stade Brestois 29 [Youth] | 1:3 | |
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| 18. Round | 26/03/2022 | Stade Lavallois [Youth] | - | Stade Brestois 29 [Youth] | 0:3 | ||||
| 24. Round | 17/04/2022 | EA Guingamp [Youth] | - | Stade Brestois 29 [Youth] | 0:1 | ||||
| 25. Round | 01/05/2022 | Stade Brestois 29 [Youth] | - | Le Mans FC [Youth] | 3:2 | |
France