| 17. Round | 05/02/2022 | Montpellier HSC B | - | Andrézieux-Bouthéon FC | 0:2 | ||||
| 18. Round | 12/02/2022 | US Colomiers | - | Montpellier HSC B | 1:1 | ||||
| 19. Round | 18/02/2022 | Montpellier HSC B | - | FC Nantes B | 0:0 | ||||
| 25. Round | 16/04/2022 | Montpellier HSC B | - | Stade Montois | 4:0 | ||||
| 26. Round | 23/04/2022 | Bourges Foot 18 | - | Montpellier HSC B | 2:1 |  |
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| 27. Round | 30/04/2022 | Montpellier HSC B | - | Le Puy Foot 43 | 1:3 |
France