| 6. Round | 11/09/2021 | SM Caen B | - | SO Romorantin | 0:0 | ||||
| 7. Round | 18/09/2021 | SO Romorantin | - | FC Rouen 1899 | 1:1 | ||||
| 8. Round | 25/09/2021 | AS Vitré | - | SO Romorantin | 1:1 | ||||
| 9. Round | 09/10/2021 | SO Romorantin | - | FC Versailles | 1:3 | ||||
| 10. Round | 23/10/2021 | US Saint-Malo | - | SO Romorantin | 0:2 | ||||
| 11. Round | 06/11/2021 | SO Romorantin | - | Stade Plabennec | 1:0 | ||||
| 12. Round | 20/11/2021 | St-Pryvé St-Hilaire | - | SO Romorantin | 1:0 | ||||
| 13. Round | 04/12/2021 | SO Romorantin | - | Blois Foot 41 | 1:1 | ||||
| 14. Round | 11/12/2021 | FC Lorient B | - | SO Romorantin | 4:0 |
France