| 23. Round | 05/02/2010 | CS Sedan | - | RC Strasbourg | 3:3 | ||||
| 24. Round | 15/02/2010 | RC Strasbourg | - | FC Nantes | 1:0 | ||||
| 25. Round | 19/02/2010 | RC Strasbourg | - | Clermont Foot Auvergne 63 | 1:1 |  |
|||
| 27. Round | 05/03/2010 | RC Strasbourg | - | Angers SCO | 1:2 | ||||
| 28. Round | 12/03/2010 | Vannes OC | - | RC Strasbourg | 1:1 | ||||
| 29. Round | 19/03/2010 | RC Strasbourg | - | Stade Brestois 29 | 1:0 | ||||
| 30. Round | 26/03/2010 | Tours FC | - | RC Strasbourg | 2:0 | ||||
| 31. Round | 05/04/2010 | RC Strasbourg | - | FC Metz | 1:1 |  |
|||
| 32. Round | 09/04/2010 | FC Istres | - | RC Strasbourg | 2:0 | ||||
| 33. Round | 16/04/2010 | RC Strasbourg | - | Dijon FCO | 3:1 | ||||
| 34. Round | 23/04/2010 | SC Bastia | - | RC Strasbourg | 1:0 | ||||
| 35. Round | 30/04/2010 | RC Strasbourg | - | Nîmes Olympique | 1:1 | ||||
| 36. Round | 04/05/2010 | EA Guingamp | - | RC Strasbourg | 2:0 | ||||
| 37. Round | 07/05/2010 | RC Strasbourg | - | Havre AC | 1:1 | ||||
| 38. Round | 14/05/2010 | LB Châteauroux | - | RC Strasbourg | 2:1 |
Senegal