| 17. Round | 05/02/2022 | SC Schiltigheim | - | Olympique Saint-Quentin | 1:1 | ||||
| 19. Round | 19/02/2022 | SC Schiltigheim | - | FC Fleury 91 | 0:1 | ||||
| 18. Round | 26/02/2022 | RC Lens B | - | SC Schiltigheim | 1:1 | ||||
| 20. Round | 05/03/2022 | US Lusitanos | - | SC Schiltigheim | 0:0 | ||||
| 21. Round | 12/03/2022 | SC Schiltigheim | - | FC Metz B | 1:1 | ||||
| 22. Round | 19/03/2022 | SC Schiltigheim | - | AS Beauvais | 0:1 | ||||
| 23. Round | 26/03/2022 | Entente SSG | - | SC Schiltigheim | 1:0 | ||||
| 24. Round | 09/04/2022 | SC Schiltigheim | - | SAS Épinal | 1:1 | ||||
| 25. Round | 15/04/2022 | ASM Belfort | - | SC Schiltigheim | 0:0 | ||||
| 26. Round | 23/04/2022 | SC Schiltigheim | - | Sainte-Geneviève-des-Bois | 0:0 | ||||
| 27. Round | 30/04/2022 | Stade de Reims B | - | SC Schiltigheim | 2:2 | ||||
| 28. Round | 14/05/2022 | SC Schiltigheim | - | AJ Auxerre B | 2:0 | ||||
| 29. Round | 21/05/2022 | FCSR Haguenau | - | SC Schiltigheim | 4:1 | ||||
| 30. Round | 28/05/2022 | SC Schiltigheim | - | Paris 13 Atletico | 0:1 |
France