| 5. Round | 26/09/2021 | Chamois Niortais [Youth B] | - | SO Cholet [Youth B] | 3:2 | ||||
| 7. Round | 09/10/2021 | La Roche VF [Youth B] | - | SO Cholet [Youth B] | 2:1 | ||||
| 9. Round | 23/10/2021 | Angoulême CFC [Youth B] | - | SO Cholet [Youth B] | 1:2 | ||||
| 12. Round | 28/11/2021 | SO Cholet [Youth B] | - | Angers SCO [Youth B] | 2:4 | ||||
| 13. Round | 04/12/2021 | LB Châteauroux [Youth B] | - | SO Cholet [Youth B] | 2:1 |  |
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| 15. Round | 22/01/2022 | SO Cholet [Youth B] | - | Stade Rennais [Youth B] | 2:2 | ||||
| 14. Round | 29/01/2022 | FC Lorient [Youth B] | - | SO Cholet [Youth B] | 5:2 | ||||
| 16. Round | 05/02/2022 | Stade brestois 29 [Youth B] | - | SO Cholet [Youth B] | 3:1 |
France