| 1. Round | 14/08/2021 | Hatayspor | - | Kasımpaşa SK | 1:1 | ||||
| 8. Round | 03/10/2021 | Yeni Malatyaspor | - | Hatayspor | 0:2 | ||||
| 15. Round | 05/12/2021 | Hatayspor | - | İstanbul Başakşehir | 0:3 | ||||
| 17. Round | 18/12/2021 | Trabzonspor | - | Hatayspor | 2:0 | ||||
| 20. Round | 08/01/2022 | Kasımpaşa SK | - | Hatayspor | 3:1 | ||||
| 26. Round | 20/02/2022 | Fenerbahçe | - | Hatayspor | 2:0 | ||||
| 28. Round | 07/03/2022 | Gaziantep FK | - | Hatayspor | 2:2 | ||||
| 30. Round | 19/03/2022 | Beşiktaş | - | Hatayspor | 1:1 | ||||
| 31. Round | 04/04/2022 | Hatayspor | - | Adana Demirspor | 0:0 |  |
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| 32. Round | 11/04/2022 | Antalyaspor | - | Hatayspor | 4:1 | ||||
| 33. Round | 16/04/2022 | Hatayspor | - | Sivasspor | 1:1 | ||||
| 34. Round | 24/04/2022 | İstanbul Başakşehir | - | Hatayspor | 3:0 | ||||
| 35. Round | 30/04/2022 | Hatayspor | - | Altay Izmir | 0:1 | |
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| 36. Round | 06/05/2022 | Hatayspor | - | Trabzonspor | 1:1 | ||||
| 37. Round | 15/05/2022 | Konyaspor | - | Hatayspor | 3:1 | ||||
| 38. Round | 22/05/2022 | Hatayspor | - | Giresunspor | 4:1 |  |
Turkey