| 1. Round | 03/06/2022 | Tigre II | - | Unión de Santa Fe II | 0:3 | ||||
| 2. Round | 08/06/2022 | Barracas Central II | - | Tigre II | 1:2 |  |
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| 3. Round | 13/06/2022 | Tigre II | - | Boca Juniors II | 0:2 | ||||
| 4. Round | 18/06/2022 | Banfield II | - | Tigre II | 0:0 | ||||
| 5. Round | 25/06/2022 | Tigre II | - | San Lorenzo II | 3:2 | |
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| 6. Round | 03/07/2022 | Talleres de Córdoba II | - | Tigre II | 0:2 | ||||
| 7. Round | 10/07/2022 | Tigre II | - | Argentinos Juniors II | 1:0 | ||||
| 9. Round | 19/07/2022 | Tigre II | - | Patronato de Paraná II | 1:1 | ||||
| 10. Round | 24/07/2022 | Platense II | - | Tigre II | 1:1 | ||||
| 11. Round | 30/07/2022 | Tigre II | - | Racing Club II | 1:0 | ||||
| 12. Round | 06/08/2022 | Rosario Central II | - | Tigre II | 2:0 | ||||
| 13. Round | 13/08/2022 | Tigre II | - | Defensa y Justicia II | 2:3 | ||||
| 23. Round | 05/10/2022 | Tigre II | - | Sarmiento de Junín II | 1:1 | ||||
| 26. Round | 17/10/2022 | Tigre II | - | Central Córdoba SdE II | 1:0 | ||||
| 27. Round | 23/10/2022 | Arsenal de Sarandí II | - | Tigre II | 0:0 |
Argentina