| 5. Round | 04/09/2021 | Louhans-Cuiseaux | - | GFA Rumilly Vallières | 2:0 | ||||
| 6. Round | 11/09/2021 | AS Saint-Priest | - | Louhans-Cuiseaux | 0:2 | ||||
| 9. Round | 09/10/2021 | Louhans-Cuiseaux | - | Aubagne FC | 3:2 | ||||
| 16. Round | 22/01/2022 | Louhans-Cuiseaux | - | Lyon-La Duchère | 1:0 | ||||
| 15. Round | 29/01/2022 | SC Toulon | - | Louhans-Cuiseaux | 1:2 | ||||
| 17. Round | 05/02/2022 | AS Monaco B | - | Louhans-Cuiseaux | 1:1 | ||||
| 19. Round | 19/02/2022 | GFA Rumilly Vallières | - | Louhans-Cuiseaux | 0:3 | ||||
| 18. Round | 26/02/2022 | Louhans-Cuiseaux | - | FC Martigues | 0:2 | ||||
| 20. Round | 05/03/2022 | Louhans-Cuiseaux | - | AS Saint-Priest | 0:1 | ||||
| 21. Round | 12/03/2022 | Étoile FC | - | Louhans-Cuiseaux | 2:1 | ||||
| 26. Round | 23/04/2022 | Louhans-Cuiseaux | - | Marignane Gignac FC | 0:0 |
France