| 5. Round | 12/09/2010 | Olympique Marseille | - | AS Monaco | 2:2 | ||||
| 6. Round | 18/09/2010 | AS Monaco | - | Toulouse FC | 0:0 | ||||
| 8. Round | 02/10/2010 | AS Monaco | - | Stade Brestois 29 | 0:1 | ||||
| 11. Round | 02/11/2010 | AS Monaco | - | Girondins Bordeaux | 2:2 | ||||
| 12. Round | 07/11/2010 | AS Nancy Lorraine | - | AS Monaco | 0:4 |  |
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| 13. Round | 13/11/2010 | AS Monaco | - | AC Arles-Avignon | 0:0 | ||||
| 14. Round | 21/11/2010 | Lille OSC | - | AS Monaco | 2:1 | ||||
| 15. Round | 27/11/2010 | AS Monaco | - | OGC Nice | 1:1 | ||||
| 16. Round | 04/12/2010 | Stade Rennais | - | AS Monaco | 1:0 | ||||
| 17. Round | 12/12/2010 | AS Monaco | - | AS Saint-Étienne | 0:2 | ||||
| 18. Round | 18/12/2010 | Paris Saint-Germain | - | AS Monaco | 2:2 | ||||
| 19. Round | 22/12/2010 | AS Monaco | - | FC Sochaux | 2:1 |  |
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| 35. Round | 11/05/2011 | FC Sochaux | - | AS Monaco | 3:0 | ||||
| 36. Round | 15/05/2011 | AS Monaco | - | RC Lens | 1:1 | ||||
| 37. Round | 21/05/2011 | Montpellier HSC | - | AS Monaco | 0:1 | ||||
| 38. Round | 29/05/2011 | AS Monaco | - | Olympique Lyonnais | 0:2 |
France