| 1. Round | 28/07/2000 | SM Caen | - | AS Cannes | 2:2 | ||||
| 2. Round | 04/08/2000 | Montpellier HSC | - | SM Caen | 2:0 | ||||
| 11. Round | 22/09/2000 | SM Caen | - | OGC Nice | 1:0 | ||||
| 12. Round | 29/09/2000 | Nîmes Olympique | - | SM Caen | 1:2 |  |
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| 13. Round | 06/10/2000 | SM Caen | - | AS Beauvais | 1:1 |  |
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| 14. Round | 10/10/2000 | SM Caen | - | AC Ajaccio | 2:0 | |
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| 15. Round | 13/10/2000 | Chamois Niortais | - | SM Caen | 2:0 | ||||
| 16. Round | 20/10/2000 | SM Caen | - | LB Châteauroux | 1:1 | ||||
| 18. Round | 03/11/2000 | SM Caen | - | Le Mans UC 72 | 0:2 | ||||
| 19. Round | 10/11/2000 | Angers SCO | - | SM Caen | 0:1 | ||||
| 20. Round | 17/11/2000 | SM Caen | - | Montpellier HSC | 0:0 | ||||
| 21. Round | 28/11/2000 | FC Sochaux | - | SM Caen | 3:0 | ||||
| 25. Round | 13/01/2001 | AS Nancy Lorraine | - | SM Caen | 4:0 | ||||
| 26. Round | 26/01/2001 | SM Caen | - | ES Wasquehal | 1:2 | ||||
| 36. Round | 27/04/2001 | Le Mans UC 72 | - | SM Caen | 1:1 | ||||
| 37. Round | 10/05/2001 | SM Caen | - | Angers SCO | 4:0 | ||||
| 38. Round | 17/05/2001 | AS Cannes | - | SM Caen | 2:0 |
France