| 8. Round | 25/09/2021 | US Saint-Malo | - | Vannes OC | 2:2 | ||||
| 9. Round | 09/10/2021 | Vannes OC | - | Stade Plabennec | 1:1 | ||||
| 14. Round | 11/12/2021 | AS Poissy | - | Vannes OC | 1:3 | ||||
| 13. Round | 26/01/2022 | Vannes OC | - | EA Guingamp B | 2:0 | ||||
| 15. Round | 29/01/2022 | Vannes OC | - | C'Chartres Football | 2:3 | ||||
| 17. Round | 05/02/2022 | US Granvillaise | - | Vannes OC | 1:2 | ||||
| 22. Round | 19/03/2022 | Vannes OC | - | US Saint-Malo | 3:2 |  |
|||
| 23. Round | 26/03/2022 | Stade Plabennec | - | Vannes OC | 1:0 | ||||
| 26. Round | 23/04/2022 | Vannes OC | - | FC Lorient B | 0:3 | ||||
| 27. Round | 30/04/2022 | EA Guingamp B | - | Vannes OC | 1:0 | ||||
| 28. Round | 14/05/2022 | Vannes OC | - | AS Poissy | 1:1 | ||||
| 29. Round | 21/05/2022 | C'Chartres Football | - | Vannes OC | 1:1 | ||||
| 30. Round | 28/05/2022 | Vannes OC | - | Châteaubriant Voltigeurs | 1:2 |
France