| 18. Round | 31/01/2021 | Espanyol Barcelona [Women] | - | EDF Logroño [Women] | 1:0 | ||||
| 16. Round | 14/02/2021 | Rayo Vallecano [Women] | - | Espanyol Barcelona [Women] | 2:0 | ||||
| 20. Round | 17/03/2021 | Espanyol Barcelona [Women] | - | UDG Tenerife Sur [Women] | 2:3 | ||||
| 23. Round | 20/03/2021 | SD Eibar [Women] | - | Espanyol Barcelona [Women] | 0:1 | ||||
| 24. Round | 28/03/2021 | Espanyol Barcelona [Women] | - | Real Sociedad [Women] | 0:4 | ||||
| 25. Round | 04/04/2021 | Real Betis [Women] | - | Espanyol Barcelona [Women] | 0:0 | ||||
| 26. Round | 17/04/2021 | Espanyol Barcelona [Women] | - | Rayo Vallecano [Women] | 2:2 | ||||
| 27. Round | 25/04/2021 | Sporting de Huelva [Women] | - | Espanyol Barcelona [Women] | 2:1 | ||||
| 28. Round | 02/05/2021 | Valencia CF [Women] | - | Espanyol Barcelona [Women] | 2:1 |  |
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| 31. Round | 22/05/2021 | Espanyol Barcelona [Women] | - | FC Barcelona [Women] | 2:3 | ||||
| 32. Round | 05/06/2021 | Atlético Madrid [Women] | - | Espanyol Barcelona [Women] | 4:1 | |
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| 33. Round | 19/06/2021 | Espanyol Barcelona [Women] | - | Madrid CFF [Women] | 3:3 | ||||
| 34. Round | 26/06/2021 | Sevilla FC [Women] | - | Espanyol Barcelona [Women] | 2:1 |
Spain