| 32. Round | 20/03/2022 | CD Leganés | - | Sporting Gijón | 1:1 | ||||
| 33. Round | 26/03/2022 | Sporting Gijón | - | FC Cartagena | 4:1 | ||||
| 34. Round | 03/04/2022 | Burgos CF | - | Sporting Gijón | 0:0 | ||||
| 35. Round | 09/04/2022 | AD Alcorcón | - | Sporting Gijón | 1:1 | ||||
| 36. Round | 16/04/2022 | Sporting Gijón | - | Real Oviedo | 0:1 | ||||
| 37. Round | 25/04/2022 | UD Almería | - | Sporting Gijón | 1:0 | ||||
| 38. Round | 01/05/2022 | Sporting Gijón | - | UD Ibiza | 0:1 | ||||
| 39. Round | 07/05/2022 | SD Huesca | - | Sporting Gijón | 1:1 | ||||
| 40. Round | 15/05/2022 | Sporting Gijón | - | Girona FC | 2:1 | ||||
| 41. Round | 21/05/2022 | CF Fuenlabrada | - | Sporting Gijón | 0:0 |
Spain