| 11. Round | 06/11/2021 | Canet Roussillon | - | Bergerac Périgord FC | 0:3 | ||||
| 12. Round | 20/11/2021 | Canet Roussillon | - | Angoulême CFC | 0:0 | ||||
| 13. Round | 04/12/2021 | Trélissac FC | - | Canet Roussillon | 0:1 | ||||
| 14. Round | 11/12/2021 | Canet Roussillon | - | Moulins Yzeure Foot | 1:2 | ||||
| 19. Round | 19/02/2022 | Vendée Les Herbiers | - | Canet Roussillon | 0:1 | ||||
| 21. Round | 12/03/2022 | FC Chamalières | - | Canet Roussillon | 0:0 | ||||
| 22. Round | 19/03/2022 | Canet Roussillon | - | Andrézieux-Bouthéon FC | 0:2 | ||||
| 23. Round | 26/03/2022 | US Colomiers | - | Canet Roussillon | 2:3 | ||||
| 24. Round | 09/04/2022 | Canet Roussillon | - | FC Nantes B | 1:0 | ||||
| 25. Round | 16/04/2022 | Bergerac Périgord FC | - | Canet Roussillon | 2:1 | ||||
| 26. Round | 23/04/2022 | Angoulême CFC | - | Canet Roussillon | 1:3 | ||||
| 27. Round | 30/04/2022 | Canet Roussillon | - | Trélissac FC | 1:2 | ||||
| 28. Round | 14/05/2022 | Moulins Yzeure Foot | - | Canet Roussillon | 1:2 | ||||
| 29. Round | 21/05/2022 | Canet Roussillon | - | AS Béziers | 4:1 |
France