| 1. Round | 29/08/2021 | AJ Auxerre [Youth B] | - | FC Bourg-Péronnas [Youth B] | 5:1 | ||||
| 7. Round | 10/10/2021 | FC Mulhouse [Youth B] | - | FC Bourg-Péronnas [Youth B] | 2:3 | ||||
| 8. Round | 17/10/2021 | FC Bourg-Péronnas [Youth B] | - | SAS Épinal [Youth B] | 2:0 | ||||
| 9. Round | 24/10/2021 | AS Nancy Lorraine [Youth B] | - | FC Bourg-Péronnas [Youth B] | 5:0 | ||||
| 10. Round | 13/11/2021 | FC Bourg-Péronnas [Youth B] | - | RC Strasbourg [Youth B] | 0:2 | ||||
| 12. Round | 28/11/2021 | FC Lyon [Youth B] | - | FC Bourg-Péronnas [Youth B] | 0:1 | ||||
| 13. Round | 04/12/2021 | FC Bourg-Péronnas [Youth B] | - | Racing Besançon [Youth B] | 3:0 | ||||
| 14. Round | 16/01/2022 | FC Metz [Youth B] | - | FC Bourg-Péronnas [Youth B] | 3:1 | ||||
| 16. Round | 06/02/2022 | FC Sochaux [Youth B] | - | FC Bourg-Péronnas [Youth B] | 2:0 | ||||
| 21. Round | 27/03/2022 | FC Bourg-Péronnas [Youth B] | - | AS Nancy Lorraine [Youth B] | 3:3 |
France