| 2. Round | 23/08/2021 | Getafe CF | - | Sevilla FC | 0:1 | ||||
| 3. Round | 29/08/2021 | FC Barcelona | - | Getafe CF | 2:1 | ||||
| 4. Round | 13/09/2021 | Getafe CF | - | Elche CF | 0:1 | ||||
| 7. Round | 26/09/2021 | Real Betis | - | Getafe CF | 2:0 |  |
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| 9. Round | 16/10/2021 | Levante UD | - | Getafe CF | 0:0 | |
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| 10. Round | 25/10/2021 | Getafe CF | - | RC Celta | 0:3 | ||||
| 11. Round | 28/10/2021 | Granada CF | - | Getafe CF | 1:1 |
Spain