| 8. Round | 25/09/2021 | Montpellier HSC B | - | Trélissac FC | 1:2 | ||||
| 17. Round | 05/02/2022 | Montpellier HSC B | - | Andrézieux-Bouthéon FC | 0:2 | ||||
| 18. Round | 12/02/2022 | US Colomiers | - | Montpellier HSC B | 1:1 |  |
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| 19. Round | 18/02/2022 | Montpellier HSC B | - | FC Nantes B | 0:0 | |
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| 21. Round | 12/03/2022 | Montpellier HSC B | - | Angoulême CFC | 0:0 | ||||
| 22. Round | 19/03/2022 | Trélissac FC | - | Montpellier HSC B | 3:0 | ||||
| 24. Round | 09/04/2022 | AS Béziers | - | Montpellier HSC B | 2:2 |
France
Portugal