| 4. Round | 12/09/2021 | USSA Vertou [Youth] | - | Le Mans FC [Youth] | 0:1 | ||||
| 5. Round | 19/09/2021 | SA Mérignac [Youth] | - | USSA Vertou [Youth] | 3:1 | ||||
| 6. Round | 26/09/2021 | Tours FC [Youth] | - | USSA Vertou [Youth] | 0:3 | ||||
| 8. Round | 09/10/2021 | FC Nantes [Youth] | - | USSA Vertou [Youth] | 3:1 | ||||
| 9. Round | 17/10/2021 | USSA Vertou [Youth] | - | Angers SCO [Youth] | 1:1 | ||||
| 10. Round | 24/10/2021 | LB Châteauroux [Youth] | - | USSA Vertou [Youth] | 0:1 | ||||
| 11. Round | 14/11/2021 | USSA Vertou [Youth] | - | US Avranches [Youth] | 0:3 | ||||
| 12. Round | 21/11/2021 | US Concarneau [Youth] | - | USSA Vertou [Youth] | 2:1 |
France