| 1. Round | 12/02/2022 | Banfield | - | San Lorenzo | 0:0 | ||||
| 2. Round | 17/02/2022 | Sarmiento de Junín | - | Banfield | 2:2 | ||||
| 4. Round | 26/02/2022 | Platense | - | Banfield | 0:1 |  |
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| 6. Round | 13/03/2022 | Unión de Santa Fe | - | Banfield | 2:1 | ||||
| 7. Round | 19/03/2022 | Lanús | - | Banfield | 0:1 |  |
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| 9. Round | 10/04/2022 | Patronato de Paraná | - | Banfield | 0:1 | ||||
| 10. Round | 18/04/2022 | Banfield | - | River Plate | 1:2 | ||||
| 11. Round | 20/04/2022 | Newell's Old Boys | - | Banfield | 1:0 | |
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| 12. Round | 24/04/2022 | Banfield | - | Talleres de Córdoba | 3:1 | ||||
| 14. Round | 10/05/2022 | Banfield | - | Atlético Tucumán | 1:1 | |
Argentina