| 7. Round | 06/12/2020 | Extremadura UD | - | Mérida AD | 1:1 | ||||
| 8. Round | 13/12/2020 | UD Melilla | - | Extremadura UD | 0:0 | ||||
| 13. Round | 06/02/2021 | Extremadura UD | - | CP Villarrobledo | 3:1 | ||||
| 11. Round | 10/02/2021 | Villarrubia CF | - | Extremadura UD | 1:1 | ||||
| 14. Round | 14/02/2021 | CF Talavera | - | Extremadura UD | 2:2 | ||||
| 15. Round | 21/02/2021 | Extremadura UD | - | CF Villanovense | 1:0 |  |
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| 16. Round | 07/03/2021 | Mérida AD | - | Extremadura UD | 0:1 | ||||
| 17. Round | 14/03/2021 | Extremadura UD | - | UD Melilla | 2:1 | ||||
| 18. Round | 21/03/2021 | UD Socuéllamos | - | Extremadura UD | 1:3 |
Ghana