| 3. Round | 21/08/2021 | RC Lens B | - | FC Metz B | 0:2 | ||||
| 4. Round | 28/08/2021 | FC Metz B | - | FC Fleury 91 | 1:3 |  |
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| 5. Round | 04/09/2021 | US Lusitanos | - | FC Metz B | 3:1 | |
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| 6. Round | 11/09/2021 | AS Beauvais | - | FC Metz B | 1:0 | ||||
| 8. Round | 25/09/2021 | Entente SSG | - | FC Metz B | 2:4 | ||||
| 12. Round | 20/11/2021 | Stade de Reims B | - | FC Metz B | 1:3 | ||||
| 13. Round | 04/12/2021 | FC Metz B | - | AJ Auxerre B | 0:2 | ||||
| 14. Round | 08/01/2022 | FCSR Haguenau | - | FC Metz B | 2:1 | ||||
| 15. Round | 15/01/2022 | FC Metz B | - | Paris 13 Atletico | 0:3 |
France