| 2. Round | 04/09/2021 | Castelnau Le Crès FC [Youth B] | - | Gazélec FC Ajaccio [Youth B] | 4:1 | ||||
| 4. Round | 19/09/2021 | Olympique Marseille [Youth B] | - | Gazélec FC Ajaccio [Youth B] | 1:1 | ||||
| 6. Round | 03/10/2021 | AC Ajaccio [Youth B] | - | Gazélec FC Ajaccio [Youth B] | 2:0 | ||||
| 11. Round | 20/11/2021 | Gazélec FC Ajaccio [Youth B] | - | OGC Nice [Youth B] | 1:0 | ||||
| 12. Round | 28/11/2021 | Clermont Foot 63 [Youth B] | - | Gazélec FC Ajaccio [Youth B] | 0:1 | ||||
| 14. Round | 15/01/2022 | Gazélec FC Ajaccio [Youth B] | - | Castelnau Le Crès FC [Youth B] | 1:0 | ||||
| 15. Round | 23/01/2022 | Andrézieux-Bouthéon FC [Youth B] | - | Gazélec FC Ajaccio [Youth B] | 4:0 | ||||
| 17. Round | 12/02/2022 | Olympique de Valence [Youth B] | - | Gazélec FC Ajaccio [Youth B] | 2:1 | ||||
| 19. Round | 13/03/2022 | Racing FC Toulon [Youth B] | - | Gazélec FC Ajaccio [Youth B] | 2:2 | ||||
| 23. Round | 09/04/2022 | OGC Nice [Youth B] | - | Gazélec FC Ajaccio [Youth B] | 2:0 | ||||
| 25. Round | 01/05/2022 | SC Air Bel [Youth B] | - | Gazélec FC Ajaccio [Youth B] | 3:4 |
France