| 1. Round | 29/08/2021 | Pau FC [Youth B] | - | AC Vedène [Youth B] | 1:2 | ||||
| 2. Round | 05/09/2021 | Nîmes Olympique [Youth B] | - | Pau FC [Youth B] | 2:2 | ||||
| 3. Round | 12/09/2021 | Pau FC [Youth B] | - | Montpellier HSC [Youth B] | 0:2 | ||||
| 4. Round | 19/09/2021 | Rodez AF [Youth B] | - | Pau FC [Youth B] | 4:0 | ||||
| 5. Round | 25/09/2021 | Pau FC [Youth B] | - | Girondins Bordeaux [Youth B] | 2:3 | ||||
| 6. Round | 02/10/2021 | Montauban FC [Youth B] | - | Pau FC [Youth B] | 3:2 | ||||
| 7. Round | 10/10/2021 | Pau FC [Youth B] | - | Balma SC [Youth B] | 0:1 | ||||
| 10. Round | 14/11/2021 | Pau FC [Youth B] | - | FC Istres [Youth B] | 4:5 | ||||
| 11. Round | 21/11/2021 | Marignane Gignac [Youth B] | - | Pau FC [Youth B] | 2:1 |
France