| 10. Round | 24/07/2022 | Defensa y Justicia II | - | Newell's Old Boys II | 1:2 | ||||
| 11. Round | 28/07/2022 | Newell's Old Boys II | - | Atlético Tucumán II | 0:0 | ||||
| 12. Round | 06/08/2022 | Colón de Santa Fe II | - | Newell's Old Boys II | 0:2 | ||||
| 13. Round | 11/08/2022 | Newell's Old Boys II | - | River Plate II | 2:0 | ||||
| 14. Round | 15/08/2022 | Lanús II | - | Newell's Old Boys II | 2:0 | ||||
| 15. Round | 21/08/2022 | Newell's Old Boys II | - | Huracán II | 2:1 | ||||
| 16. Round | 26/08/2022 | Godoy Cruz II | - | Newell's Old Boys II | 1:1 | ||||
| 17. Round | 31/08/2022 | Newell's Old Boys II | - | Vélez Sarsfield II | 0:2 | ||||
| 19. Round | 12/09/2022 | Newell's Old Boys II | - | Aldosivi II | 3:1 | ||||
| 23. Round | 03/10/2022 | Arsenal de Sarandí II | - | Newell's Old Boys II | 1:2 | ||||
| 26. Round | 18/10/2022 | Boca Juniors II | - | Newell's Old Boys II | 2:1 | ||||
| 27. Round | 22/10/2022 | Newell's Old Boys II | - | Barracas Central II | 3:0 |
Argentina