| 1° División | 03/08/19 | Atlas Guadalajara | - | Santos Laguna | 1:2 | ||||
| 1° División | 22/08/20 | Club Necaxa | - | Santos Laguna | 2:1 | ||||
| 1° División | 20/09/20 | Deportivo Toluca | - | Santos Laguna | 1:2 | ||||
| 1° División | 19/02/21 | Atlético San Luis | - | Santos Laguna | 1:0 |  |
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| 1° División | 05/11/21 | Pumas UNAM | - | Santos Laguna | 0:3 | ||||
| 1° División | 13/01/22 | Santos Laguna | - | UANL Tigres | 1:1 | ||||
| 1° División | 04/04/22 | Santos Laguna | - | CF Pachuca | 3:1 | ||||
| 1° División | 26/08/22 | Club Tijuana | - | Santos Laguna | 0:2 | ||||
| 1° División | 03/10/22 | Santos Laguna | - | Mazatlán FC | 3:0 | ||||
| 1° División | 20/03/23 | Club León | - | Santos Laguna | 4:1 | ||||
| 1° División | 07/05/23 | CF Pachuca | - | Santos Laguna | 4:4 pso |  |
Ecuador