| 1. Round | 29/08/2021 | UE Cornellà | - | Atlético Baleares | 0:2 | ||||
| 3. Round | 11/09/2021 | UE Cornellà | - | Algeciras CF | 4:0 |  |
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| 4. Round | 17/09/2021 | UE Costa Brava | - | UE Cornellà | 1:0 | |
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| 5. Round | 25/09/2021 | UE Cornellà | - | CD Castellón | 1:1 | ||||
| 6. Round | 03/10/2021 | Linares Deportivo | - | UE Cornellà | 0:3 | ||||
| 7. Round | 08/10/2021 | UE Cornellà | - | Real Madrid Castilla | 1:0 | ||||
| 12. Round | 13/11/2021 | Real Betis B | - | UE Cornellà | 1:3 | ||||
| 13. Round | 21/11/2021 | UE Cornellà | - | Sevilla Atlético | 1:2 | ||||
| 14. Round | 28/11/2021 | CD Alcoyano | - | UE Cornellà | 2:0 | ||||
| 17. Round | 19/12/2021 | UE Cornellà | - | FC Barcelona B | 1:0 |
Spain