| 17. Round | 12/12/2021 | CA Osasuna | - | FC Barcelona | 2:2 | ||||
| 18. Round | 18/12/2021 | FC Barcelona | - | Elche CF | 3:2 |  |
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| 4. Round | 21/12/2021 | Sevilla FC | - | FC Barcelona | 1:1 | ||||
| 19. Round | 02/01/2022 | RCD Mallorca | - | FC Barcelona | 0:1 |  |
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| 20. Round | 08/01/2022 | Granada CF | - | FC Barcelona | 1:1 | ||||
| 22. Round | 23/01/2022 | CD Alavés | - | FC Barcelona | 0:1 |
Spain