| 16. Round | 22/01/2022 | Canet Roussillon | - | Bourges Foot 18 | 0:2 | ||||
| 15. Round | 29/01/2022 | AS Béziers | - | Canet Roussillon | 4:0 | ||||
| 18. Round | 12/02/2022 | Canet Roussillon | - | Angers SCO B | 2:0 | ||||
| 19. Round | 19/02/2022 | Vendée Les Herbiers | - | Canet Roussillon | 0:1 | ||||
| 20. Round | 05/03/2022 | Canet Roussillon | - | Montpellier HSC B | 0:1 | ||||
| 24. Round | 09/04/2022 | Canet Roussillon | - | FC Nantes B | 1:0 |  |
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| 25. Round | 16/04/2022 | Bergerac Périgord FC | - | Canet Roussillon | 2:1 | ||||
| 26. Round | 23/04/2022 | Angoulême CFC | - | Canet Roussillon | 1:3 | ||||
| 27. Round | 30/04/2022 | Canet Roussillon | - | Trélissac FC | 1:2 | ||||
| 28. Round | 14/05/2022 | Moulins Yzeure Foot | - | Canet Roussillon | 1:2 |  |
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| 29. Round | 21/05/2022 | Canet Roussillon | - | AS Béziers | 4:1 | |
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| 30. Round | 28/05/2022 | Stade Montois | - | Canet Roussillon | 2:2 | |
France