| Group E | 19/09/2018 | AFC Ajax | - | AEK Athen | 3:0 |  |
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| Group E | 23/10/2018 | AFC Ajax | - | SL Benfica | 1:0 | ||||
| Group E | 07/11/2018 | SL Benfica | - | AFC Ajax | 1:1 | ||||
| Group E | 27/11/2018 | AEK Athen | - | AFC Ajax | 0:2 | ||||
| Group E | 12/12/2018 | AFC Ajax | - | Bayern München | 3:3 | ||||
| Round of 16 | 13/02/2019 | AFC Ajax | - | Real Madrid | 1:2 | ||||
| Round of 16 | 05/03/2019 | Real Madrid | - | AFC Ajax | 1:4 | ||||
| Quarter-finals | 10/04/2019 | AFC Ajax | - | Juventus | 1:1 | |
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| Quarter-finals | 16/04/2019 | Juventus | - | AFC Ajax | 1:2 | ||||
| Semi-finals | 30/04/2019 | Tottenham Hotspur | - | AFC Ajax | 0:1 | ||||
| Semi-finals | 08/05/2019 | AFC Ajax | - | Tottenham Hotspur | 2:3 |
Netherlands
