| 1. Round | 29/08/2021 | OGC Nice [Youth B] | - | Olympique de Valence [Youth B] | 2:0 | ||||
| 7. Round | 09/10/2021 | Olympique Marseille [Youth B] | - | Olympique de Valence [Youth B] | 1:3 | ||||
| 8. Round | 16/10/2021 | Castelnau Le Crès FC [Youth B] | - | Olympique de Valence [Youth B] | 0:2 | ||||
| 9. Round | 24/10/2021 | Olympique de Valence [Youth B] | - | AC Ajaccio [Youth B] | 2:1 | ||||
| 10. Round | 14/11/2021 | Racing FC Toulon [Youth B] | - | Olympique de Valence [Youth B] | 0:3 | ||||
| 11. Round | 21/11/2021 | Olympique de Valence [Youth B] | - | Lyon-La Duchère [Youth B] | 6:1 | ||||
| 12. Round | 27/11/2021 | AS Saint-Étienne [Youth B] | - | Olympique de Valence [Youth B] | 2:0 | ||||
| 17. Round | 12/02/2022 | Olympique de Valence [Youth B] | - | Gazélec FC Ajaccio [Youth B] | 2:1 | ||||
| 22. Round | 03/04/2022 | Olympique de Valence [Youth B] | - | Racing FC Toulon [Youth B] | 3:0 | ||||
| 23. Round | 10/04/2022 | Lyon-La Duchère [Youth B] | - | Olympique de Valence [Youth B] | 5:3 |
France