| 1. Round | 15/07/2000 | FC Luzern | - | Neuchâtel Xamax FC | 2:0 | ||||
| 3. Round | 22/07/2000 | Grasshopper Club Zürich | - | Neuchâtel Xamax FC | 6:0 | ||||
| 5. Round | 04/08/2000 | Servette FC | - | Neuchâtel Xamax FC | 5:2 | ||||
| 7. Round | 19/08/2000 | FC Lugano | - | Neuchâtel Xamax FC | 3:0 | ||||
| 8. Round | 26/08/2000 | Neuchâtel Xamax FC | - | FC Aarau | 1:5 | ||||
| 9. Round | 05/09/2000 | FC Zürich | - | Neuchâtel Xamax FC | 3:0 | ||||
| 10. Round | 09/09/2000 | Neuchâtel Xamax FC | - | Lausanne Sports | 2:4 | ||||
| 13. Round | 01/10/2000 | FC Basel 1893 | - | Neuchâtel Xamax FC | 5:1 | ||||
| 15. Round | 21/10/2000 | Yverdon Sport FC | - | Neuchâtel Xamax FC | 4:0 | ||||
| 21. Round | 02/12/2000 | Lausanne Sports | - | Neuchâtel Xamax FC | 2:0 | ||||
| 22. Round | 10/12/2000 | Neuchâtel Xamax FC | - | FC Sion | 1:0 |  |
Switzerland