| 1. Round | 06/06/2022 | Lanús II | - | Rosario Central II | 2:2 | ||||
| 2. Round | 10/06/2022 | Rosario Central II | - | Huracán II | 3:3 | ||||
| 3. Round | 15/06/2022 | Godoy Cruz II | - | Rosario Central II | 1:1 | ||||
| 5. Round | 24/06/2022 | Gimnasia de La Plata II | - | Rosario Central II | 0:1 | ||||
| 6. Round | 02/07/2022 | Rosario Central II | - | Aldosivi II | 5:1 | ||||
| 7. Round | 08/07/2022 | Sarmiento de Junín II | - | Rosario Central II | 1:2 | ||||
| 10. Round | 23/07/2022 | Rosario Central II | - | Arsenal de Sarandí II | 2:1 | ||||
| 12. Round | 06/08/2022 | Rosario Central II | - | Tigre II | 2:0 | ||||
| 13. Round | 11/08/2022 | Barracas Central II | - | Rosario Central II | 0:3 | ||||
| 14. Round | 16/08/2022 | Rosario Central II | - | Boca Juniors II | 0:6 | ||||
| 17. Round | 03/09/2022 | Talleres de Córdoba II | - | Rosario Central II | 3:2 | ||||
| 20. Round | 17/09/2022 | Rosario Central II | - | Patronato de Paraná II | 1:0 | ||||
| 23. Round | 03/10/2022 | Unión de Santa Fe II | - | Rosario Central II | 1:0 | ||||
| 26. Round | 16/10/2022 | Rosario Central II | - | River Plate II | 3:3 |  |
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| 27. Round | 23/10/2022 | Colón de Santa Fe II | - | Rosario Central II | 0:5 |
Argentina