| 1. Round | 04/06/2022 | Platense | - | Godoy Cruz | 2:1 | ||||
| 2. Round | 12/06/2022 | Godoy Cruz | - | Racing Club | 2:0 | ||||
| 3. Round | 16/06/2022 | Rosario Central | - | Godoy Cruz | 1:0 | ||||
| 4. Round | 20/06/2022 | Godoy Cruz | - | Defensa y Justicia | 2:1 |  |
|||
| 5. Round | 28/06/2022 | Atlético Tucumán | - | Godoy Cruz | 1:1 | ||||
| 6. Round | 02/07/2022 | Godoy Cruz | - | Colón de Santa Fe | 1:0 | ||||
| 7. Round | 11/07/2022 | River Plate | - | Godoy Cruz | 0:2 | ||||
| 8. Round | 17/07/2022 | Godoy Cruz | - | Lanús | 2:1 | ||||
| 9. Round | 21/07/2022 | Huracán | - | Godoy Cruz | 0:0 | ||||
| 10. Round | 26/07/2022 | Unión de Santa Fe | - | Godoy Cruz | 2:1 |  |
|||
| 19. Round | 13/09/2022 | Godoy Cruz | - | Tigre | 1:1 | ||||
| 26. Round | 16/10/2022 | Godoy Cruz | - | Patronato de Paraná | 0:1 |
Argentina