| 1. Round | 17/01/2016 | San Luis | - | Cobresal | 0:0 | ||||
| 2. Round | 22/01/2016 | Santiago Wanderers | - | San Luis | 3:1 | ||||
| 5. Round | 14/02/2016 | San Luis | - | Deportes Iquique | 3:1 | ||||
| 6. Round | 21/02/2016 | Unión Española | - | San Luis | 3:1 | ||||
| 7. Round | 27/02/2016 | Colo-Colo | - | San Luis | 2:0 |  |
|||
| 8. Round | 05/03/2016 | San Luis | - | Universidad de Concepción | 2:2 | ||||
| 9. Round | 14/03/2016 | Palestino | - | San Luis | 2:2 | ||||
| 10. Round | 20/03/2016 | San Luis | - | San Marcos | 1:1 | |
|||
| 11. Round | 05/04/2016 | Huachipato | - | San Luis | 3:3 | |
|||
| 12. Round | 10/04/2016 | San Luis | - | Unión La Calera | 3:1 | ||||
| 13. Round | 21/04/2016 | O'Higgins | - | San Luis | 4:3 | |
|||
| 14. Round | 27/04/2016 | San Luis | - | Universidad Católica | 1:0 | ||||
| 15. Round | 30/04/2016 | Antofagasta | - | San Luis | 1:1 |
Chile