| 3. Round | 07/08/2022 | KAA Gent | - | KVC Westerlo | 2:1 | ||||
| 5. Round | 01/09/2022 | RSC Anderlecht | - | KAA Gent | 0:1 | ||||
| 8. Round | 11/09/2022 | KAA Gent | - | SV Zulte Waregem | 2:0 | ||||
| 11. Round | 09/10/2022 | KAS Eupen | - | KAA Gent | 0:4 | ||||
| 14. Round | 23/10/2022 | KAA Gent | - | RFC Seraing | 2:1 | ||||
| 15. Round | 30/10/2022 | Oud-Heverlee Leuven | - | KAA Gent | 1:1 | ||||
| 16. Round | 06/11/2022 | KAA Gent | - | Club Brugge KV | 2:0 | ||||
| 17. Round | 13/11/2022 | KV Kortrijk | - | KAA Gent | 0:4 |  |
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| 18. Round | 23/12/2022 | KAA Gent | - | Standard Liège | 0:0 | ||||
| 19. Round | 07/01/2023 | Royal Antwerp FC | - | KAA Gent | 2:0 | ||||
| 20. Round | 15/01/2023 | KAA Gent | - | KV Kortrijk | 2:1 |  |
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| 21. Round | 19/01/2023 | KAA Gent | - | Sporting Charleroi | 0:0 | ||||
| 22. Round | 22/01/2023 | Sint-Truidense VV | - | KAA Gent | 0:3 | |
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| 23. Round | 29/01/2023 | Cercle Brugge | - | KAA Gent | 3:2 |
Belgium