| 1. Round | 07/08/2021 | Paris 13 Atletico | - | SC Schiltigheim | 0:0 | ||||
| 2. Round | 14/08/2021 | SC Schiltigheim | - | FC 93 Bobigny | 2:2 | ||||
| 3. Round | 21/08/2021 | Olympique Saint-Quentin | - | SC Schiltigheim | 1:1 | ||||
| 4. Round | 28/08/2021 | SC Schiltigheim | - | RC Lens B | 1:0 | ||||
| 5. Round | 04/09/2021 | FC Fleury 91 | - | SC Schiltigheim | 1:0 | ||||
| 6. Round | 11/09/2021 | SC Schiltigheim | - | US Lusitanos | 0:1 | ||||
| 7. Round | 18/09/2021 | FC Metz B | - | SC Schiltigheim | 4:1 | ||||
| 11. Round | 27/11/2021 | SC Schiltigheim | - | ASM Belfort | 2:2 | ||||
| 13. Round | 04/12/2021 | SC Schiltigheim | - | Stade de Reims B | 0:1 | ||||
| 16. Round | 22/01/2022 | FC 93 Bobigny | - | SC Schiltigheim | 1:0 | ||||
| 15. Round | 29/01/2022 | SC Schiltigheim | - | FCSR Haguenau | 1:0 | ||||
| 17. Round | 05/02/2022 | SC Schiltigheim | - | Olympique Saint-Quentin | 1:1 | ||||
| 23. Round | 26/03/2022 | Entente SSG | - | SC Schiltigheim | 1:0 | ||||
| 24. Round | 09/04/2022 | SC Schiltigheim | - | SAS Épinal | 1:1 | ||||
| 26. Round | 23/04/2022 | SC Schiltigheim | - | Sainte-Geneviève-des-Bois | 0:0 |
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