| 9. Round | 06/11/2021 | Real Sociedad [Women] | - | Real Betis [Women] | 4:0 | ||||
| 10. Round | 13/11/2021 | Atlético Madrid [Women] | - | Real Sociedad [Women] | 0:1 | ||||
| 11. Round | 21/11/2021 | Real Sociedad [Women] | - | UDG Tenerife Sur [Women] | 3:0 | ||||
| 12. Round | 05/12/2021 | Madrid CFF [Women] | - | Real Sociedad [Women] | 1:2 | ||||
| 13. Round | 12/12/2021 | Real Sociedad [Women] | - | Sporting de Huelva [Women] | 2:2 | ||||
| 14. Round | 18/12/2021 | SD Eibar [Women] | - | Real Sociedad [Women] | 2:3 | ||||
| 15. Round | 22/12/2021 | CD Alavés [Women] | - | Real Sociedad [Women] | 0:4 | ||||
| 16. Round | 09/01/2022 | Real Sociedad [Women] | - | Athletic Club [Women] | 1:0 | ||||
| 17. Round | 12/01/2022 | Valencia CF [Women] | - | Real Sociedad [Women] | 0:3 | ||||
| 19. Round | 29/01/2022 | Villarreal CF [Women] | - | Real Sociedad [Women] | 1:4 | ||||
| 18. Round | 09/02/2022 | Real Sociedad [Women] | - | FC Barcelona [Women] | 1:9 | ||||
| 22. Round | 13/02/2022 | Levante UD [Women] | - | Real Sociedad [Women] | 1:0 |
Spain