| 3. Round | 11/09/2022 | AJ Auxerre [Youth B] | - | Lille OSC [Youth B] | 0:1 | ||||
| 5. Round | 25/09/2022 | US Boulogne [Youth B] | - | Lille OSC [Youth B] | 2:2 | ||||
| 6. Round | 02/10/2022 | Lille OSC [Youth B] | - | USL Dunkerque [Youth B] | 5:0 | ||||
| 7. Round | 09/10/2022 | Montfermeil FC [Youth B] | - | Lille OSC [Youth B] | 1:1 |  |
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| 8. Round | 16/10/2022 | Paris 13 Atletico [Youth B] | - | Lille OSC [Youth B] | 1:3 | ||||
| 9. Round | 23/10/2022 | Lille OSC [Youth B] | - | Stade de Reims [Youth B] | 0:1 | ||||
| 12. Round | 20/11/2022 | RC Lens [Youth B] | - | Lille OSC [Youth B] | 1:1 | |
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| 13. Round | 27/11/2022 | Lille OSC [Youth B] | - | Red Star FC [Youth B] | 1:1 | ||||
| 15. Round | 15/01/2023 | Lille OSC [Youth B] | - | AJ Auxerre [Youth B] | 1:2 | ||||
| 16. Round | 22/01/2023 | AS Jeunesse Aubervilliers [Youth B] | - | Lille OSC [Youth B] | 1:4 |  |
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| 18. Round | 12/02/2023 | USL Dunkerque [Youth B] | - | Lille OSC [Youth B] | 0:3 |
France