| 3. Round | 12/09/2021 | AS Vitré [Youth B] | - | FC Rouen 1899 [Youth B] | 0:5 | ||||
| 4. Round | 19/09/2021 | US Avranches [Youth B] | - | FC Rouen 1899 [Youth B] | 3:1 | ||||
| 5. Round | 26/09/2021 | FC Rouen 1899 [Youth B] | - | Montrouge FC [Youth B] | 0:0 | ||||
| 6. Round | 03/10/2021 | Paris FC [Youth B] | - | FC Rouen 1899 [Youth B] | 2:1 | ||||
| 8. Round | 17/10/2021 | Tours FC [Youth B] | - | FC Rouen 1899 [Youth B] | 1:2 | ||||
| 9. Round | 24/10/2021 | FC Rouen 1899 [Youth B] | - | CS Brétigny [Youth B] | 3:0 | ||||
| 13. Round | 05/12/2021 | FC Rouen 1899 [Youth B] | - | Paris Saint-Germain [Youth B] | 1:1 | ||||
| 17. Round | 13/02/2022 | Montrouge FC [Youth B] | - | FC Rouen 1899 [Youth B] | 5:3 | ||||
| 15. Round | 20/02/2022 | FC Rouen 1899 [Youth B] | - | AS Vitré [Youth B] | 4:0 | ||||
| 19. Round | 13/03/2022 | US Orléans [Youth B] | - | FC Rouen 1899 [Youth B] | 3:2 | ||||
| 20. Round | 20/03/2022 | FC Rouen 1899 [Youth B] | - | Tours FC [Youth B] | 2:1 | ||||
| 21. Round | 27/03/2022 | CS Brétigny [Youth B] | - | FC Rouen 1899 [Youth B] | 4:1 |
France