| 2. Round | 04/09/2021 | SO Cholet [Youth B] | - | FC Lorient [Youth B] | 3:3 | ||||
| 3. Round | 11/09/2021 | FC Lorient [Youth B] | - | USSA Vertou [Youth B] | 1:2 | ||||
| 7. Round | 09/10/2021 | EA Guingamp [Youth B] | - | FC Lorient [Youth B] | 1:2 | ||||
| 11. Round | 20/11/2021 | Vannes OC [Youth B] | - | FC Lorient [Youth B] | 2:1 | ||||
| 13. Round | 05/12/2021 | Angers SCO [Youth B] | - | FC Lorient [Youth B] | 0:3 | ||||
| 18. Round | 06/03/2022 | Chamois Niortais [Youth B] | - | FC Lorient [Youth B] | 3:0 | ||||
| 19. Round | 13/03/2022 | FC Lorient [Youth B] | - | EA Guingamp [Youth B] | 3:4 | ||||
| 21. Round | 26/03/2022 | FC Lorient [Youth B] | - | CPBB Rennes [Youth B] | 4:1 | ||||
| 22. Round | 03/04/2022 | Angoulême CFC [Youth B] | - | FC Lorient [Youth B] | 0:3 | ||||
| 23. Round | 09/04/2022 | FC Lorient [Youth B] | - | Vannes OC [Youth B] | 4:2 | ||||
| 24. Round | 16/04/2022 | FC Nantes [Youth B] | - | FC Lorient [Youth B] | 5:3 | ||||
| 25. Round | 01/05/2022 | FC Lorient [Youth B] | - | Angers SCO [Youth B] | 0:3 |
France