| 1. Round | 19/08/2012 | Wigan Athletic | - | Chelsea FC | 0:2 | ||||
| 2. Round | 25/08/2012 | Southampton FC | - | Wigan Athletic | 0:2 | ||||
| 3. Round | 01/09/2012 | Wigan Athletic | - | Stoke City | 2:2 | ||||
| 4. Round | 15/09/2012 | Manchester United | - | Wigan Athletic | 4:0 | ||||
| 5. Round | 22/09/2012 | Wigan Athletic | - | Fulham FC | 1:2 | ||||
| 6. Round | 29/09/2012 | Sunderland AFC | - | Wigan Athletic | 1:0 | ||||
| 7. Round | 06/10/2012 | Wigan Athletic | - | Everton FC | 2:2 | ||||
| 8. Round | 20/10/2012 | Swansea City | - | Wigan Athletic | 2:1 | ||||
| 9. Round | 27/10/2012 | Wigan Athletic | - | West Ham United | 2:1 |  |
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| 10. Round | 03/11/2012 | Tottenham Hotspur | - | Wigan Athletic | 0:1 | ||||
| 11. Round | 10/11/2012 | Wigan Athletic | - | West Bromwich Albion | 1:2 | ||||
| 12. Round | 17/11/2012 | Liverpool FC | - | Wigan Athletic | 3:0 | ||||
| 13. Round | 24/11/2012 | Wigan Athletic | - | Reading FC | 3:2 | ||||
| 20. Round | 29/12/2012 | Aston Villa | - | Wigan Athletic | 0:3 | |
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| 21. Round | 01/01/2013 | Wigan Athletic | - | Manchester United | 0:4 | ||||
| 22. Round | 12/01/2013 | Fulham FC | - | Wigan Athletic | 1:1 |
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